Berberine supplement bottle, front view, white label with teal accents, gray cap, 60 capsules.
Berberine supplement bottles, front and back label views, white bottles with gray caps on white background
Berberine supplement bottle, front label view showing Supplement Facts and ingredient list.
Berberine supplement bottle, back label view showing suggested use and caution text on white background.
Digestive Health

Berberine

1,200 mg of berberine HCl from Indian barberry, formulated to support healthy glucose metabolism.

$34.99 per bottle
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  • Manufactured in a US-based GMP facility
  • Real forms, real doses on the label
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The evidence

The formula, the facts, the research

About this formula

Supports healthy glucose metabolism* and healthy cholesterol and lipid levels already in the normal range.*

Kikaboni Berberine delivers 1,200 mg of berberine HCl from Berberis aristata (Indian barberry) bark and root in every two-capsule serving.

  • 1,200 mg per serving
  • 60 capsules, a 30-day supply when taken as directed
  • Non-GMO and third-party tested
  • Manufactured in a US-based, FDA-registered, GMP-certified facility

Suggested use: As a dietary supplement, take two (2) capsules once a day. For best results, take 20-30 minutes before a meal with an 8 fl oz. glass of water or as directed by your healthcare professional.

Supplement Facts: Serving size: 2 capsules. Servings per container: 30. Berberine HCl Blend 1,200 mg**: Berberine HCl (Berberis aristata)(bark), (Berberis aristata)(root). **Daily Value (DV) not established. Other ingredients: Hypromellose (Capsule), Rice Flour, Rice Maltodextrin, Magnesium Stearate.

Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What the research says

Berberine HCl (from Berberis aristata)

Evidence tier: Moderate

What it is: A bright yellow plant compound found in the bark and roots of barberry species, studied for its role in how the body handles glucose and fats.

What the research shows: A systematic review and dose-response meta-analysis of 49 randomized controlled trials found that berberine supplementation was associated with changes in several metabolic markers, including triglycerides, total and LDL cholesterol, fasting glucose, and body weight. Many of the included trials enrolled adults with existing metabolic concerns, so the findings may not carry over to people whose markers are already in a healthy range.

Typical study dose: 0.3 to 6.25 g/day for 4 to 104 weeks across the pooled trials, with the strongest lipid and weight findings at about 1 g/day. This describes what the studies used, not a recommended amount. This formula supplies a 1,200 mg berberine HCl blend per two-capsule serving.

Zamani M, Zarei M, Nikbaf-Shandiz M, Hosseini S, Shiraseb F, Asbaghi O. "The effects of berberine supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysis." Frontiers in Nutrition, 2022. PMID: 36313096. DOI: 10.3389/fnut.2022.1013055.

Supplement facts
Serving size2 capsules
Servings per container30
Berberine HCl Blend 1,200 mgBerberine HCl (Berberis aristata bark and root)
Daily Value not established
Other ingredients: Hypromellose (capsule), Rice Flour, Rice Maltodextrin, Magnesium Stearate
Questions people ask
What is berberine?
Berberine is a plant compound from the bark and root of Berberis aristata. It is taken to support healthy glucose metabolism and lipid levels already in the normal range.*
Why take it before a meal?
Berberine is studied around mealtimes, which is why the label suggests taking it 20 to 30 minutes before eating.
Can I take it with my stack?
It is part of the Weight Management, Digestive Health and Heart Health Stacks. Take it as directed on the label, once a day.
Does it upset the stomach?
Some people notice mild digestive changes when starting berberine. Taking it with water before a meal usually helps.
Who should check with a provider first?
Pregnant or nursing mothers, anyone under 18, and anyone with a known medical condition or taking prescription medication should check with their healthcare provider before starting any supplement. This matters most if you take medication for blood sugar or blood pressure.
Shipping & subscriptions

Orders ship from a US-based facility within 1 to 2 business days. Free standard shipping on orders over $100. Subscribe & save deliveries can be changed, skipped or cancelled from your account at any time.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

What's inside

Every active, at its real dose

  • 01 Ber Berberine HCl (Berberis aristata bark & root)1,200 mgGlucose & lipid metabolism

Amounts per serving. See the Supplement Facts panel for the full label.

Proven by science

By the numbers

  • 1,200 mg berberine HCl per two-capsule servingSupplement Facts panel
  • 60 vegetable capsules, a 30-day supply at the suggested servingSupplement Facts panel
  • Studied dose Research on berberine typically uses 900 to 1,500 mg a day, split around mealsExamine.com, Berberine

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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