Vitamin K2 + D3

Vitamin D3 with K2 as MK-7 and calcium, formulated to support strong bones and healthy calcium metabolism.

$25.99 per bottle
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The evidence

The formula, the facts, the research

About this formula

Supports strong bones and healthy calcium metabolism.*

Kikaboni Vitamin K2 + D3 combines vitamin D3, vitamin K2 as MK-7 and 210 mg of calcium with BioPerine® black pepper extract in a single vegetable capsule.

  • Vitamin D3 (125 mcg, 625% DV) and calcium (210 mg) per capsule
  • 60 capsules, a 30-day supply when taken as directed
  • Non-GMO and third-party tested
  • Manufactured in a US-based, FDA-registered, GMP-certified facility

Suggested use: As a dietary supplement, take one (1) capsule twice a day. For best results, take 20-30 minutes before a meal or as directed by your healthcare professional.

Supplement Facts: Serving size: 1 veggie capsule. Servings per container: 60. Vitamin D3 (cholecalciferol) 125 mcg (625% DV); Vitamin K2 (MK-7, as menaquinone)**; Calcium (as calcium carbonate) 210 mg (16% DV); BioPerine® Black Pepper Extract (Piper nigrum)(fruit) 5 mg**. **Daily Value (DV) not established. Other ingredients: Microcrystalline Cellulose, Hypromellose (vegetable capsule).

Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What the research says

Vitamin K2 + D3

Evidence tier: Moderate-to-Strong

What it is: Vitamin K2 helps direct calcium to bone rather than soft tissue; vitamin D3 supports calcium absorption. The two are commonly paired for bone health support.

What the research shows: This is the best-supported ingredient pairing in Kikaboni's research for this life stage. A systematic review and meta-analysis of 16 randomized controlled trials (6,425 participants) found vitamin K2 supplementation was associated with improved lumbar spine bone mineral density and reduced fracture incidence in postmenopausal women. A separate 3-year randomized trial found vitamin K2 supplementation improved hip bone geometry and bone strength indices in postmenopausal women. The evidence isn't unanimous — at least one smaller trial found no significant effect on bone loss in early menopause — which is why this is "moderate-to-strong" rather than definitive.

Typical study dose: Across the trials in the meta-analysis, dosing varied by form: MK-4 (menatetrenone) studies mainly used 45 mg/day, while MK-7 (menaquinone-7) studies used 180–375 mcg/day. The 3-year hip-bone trial specifically used 45 mg/day of MK-4. These describe what the studies used, not a recommended amount.

Ma ML, Ma ZJ, He YL, Sun H, Yang B, Ruan BJ, Zhan WD, Li SX, Dong H, Wang YX. "Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis: A systematic review and meta-analysis of randomized controlled trials." Frontiers in Public Health, 2022. PMC9403798.

Knapen MH, Schurgers LJ, Vermeer C. "Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women." Osteoporosis International, 2007. PMID: 17287908.

Supplement facts
Serving size1 veggie capsule
Servings per container60
Vitamin D3 (cholecalciferol) 125 mcg, 625% DV
Vitamin K2 (MK-7, as menaquenone)
Calcium (as calcium carbonate) 210 mg, 16% DV
BioPerine Black Pepper Extract (Piper nigrum fruit) 5 mg
Daily Value not established for vitamin K2 and BioPerine
Other ingredientsMicrocrystalline Cellulose, Hypromellose (vegetable capsule)
Questions people ask
Why pair D3 with K2?
Vitamin D3 supports calcium absorption and vitamin K2 supports the proteins that help direct calcium into bone. Taking them together is a common approach to bone support.*
What is MK-7?
MK-7 is a menaquinone form of vitamin K2 that stays active in the body longer than MK-4, so once or twice daily dosing is practical.
Is 625% DV of vitamin D too much?
125 mcg (5,000 IU) per capsule is within the range commonly used in adult supplementation. Follow the label serving and check with your provider if you already take vitamin D.
Can I take it with my stack?
Yes. It is part of the Menopause Support, Bone & Joint and Immune Support Stacks and pairs well with Magnesium Glycinate.
Who should check with a provider first?
Pregnant or nursing mothers, anyone under 18, and anyone with a known medical condition or taking prescription medication should check with their healthcare provider before starting any supplement. Vitamin K interacts with blood-thinning medication, so check first if you take one.
Shipping & subscriptions

Orders ship from a US-based facility within 1 to 2 business days. Free standard shipping on orders over $100. Subscribe & save deliveries can be changed, skipped or cancelled from your account at any time.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

What's inside

Every active, at its real dose

  • 01 D3 Vitamin D3 (cholecalciferol)125 mcg (5,000 IU)Calcium absorption, 625% DV
  • 02 K2 Vitamin K2 (MK-7, menaquinone)IncludedDirects calcium to bone
  • 03 Ca Calcium (as calcium carbonate)210 mgBone mineral, 16% DV
  • 04 Pip BioPerine black pepper extract5 mgSupports absorption

Amounts per serving. See the Supplement Facts panel for the full label.

Proven by science

By the numbers

  • 125 mcg vitamin D3 per capsule, 625% of the Daily ValueSupplement Facts panel
  • MK-7 the long-acting form of vitamin K2 used in this formulaSupplement Facts panel
  • D3 + K2 Vitamin D supports calcium absorption and vitamin K supports the proteins that bind calcium into boneNIH Office of Dietary Supplements, Vitamin D and Vitamin K fact sheets

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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